Download Files:
Products Details
Product Description
– SOS1-IN-6 (compound 33-P1) is a potent SOS1 inhibitor with IC50s of 14.9 and 73.3 nM for SOS1-G12D and SOS1-G12V, respectively[1].
Web ID
– HY-144210
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C26H28F3N3O2
References
– [1]Fused quinazoline derivative, preparation method therefor and application thereof in medicine. WO2021249475A1.
CAS Number
– 2751718-88-2
Molecular Weight
– 471.51
SMILES
– O[C@H]1CC[C@H](C2=CC3=C(N[C@@H](C4=CC=CC(C(F)F)=C4F)C)N=C(C)N=C3C5=C2OCC5)CC1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Ras
Isoform
– K-Ras
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
