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Sofiniclin
$432 – $1,596
Products Details
Product Description
– Sofiniclin (ABT 894), an agonist of nicotinic acetylcholine receptor (nAChR), is used as a potential non-stimulant research for attention-deficit/hyperactivity disorder (ADHD)[1][2].
Web ID
– HY-14824
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C10H11Cl2N3
References
– [1]Zhang D, et al. ABT-089 and ABT-894 reduce levodopa-induced dyskinesias in a monkey model of Parkinson’s disease. Mov Disord. 2014 Apr;29(4):508-17.|[2]Zhang D, ET AL. α7 nicotinic receptor agonists reduce levodopa-induced dyskinesias with severe nigrostriatal damage. Mov Disord. 2015 Dec;30(14):1901-11.
CAS Number
– 799279-80-4
Molecular Weight
– 244.12
Compound Purity
– 98.54
SMILES
– ClC1=C(Cl)C=C(N2C[C@]3([H])CN[C@]3([H])C2)C=N1
Clinical Information
– Phase 2
Research Area
– Neurological Disease
Solubility
– DMSO : 35.71 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– nAChR
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
