Download Files:
Sodium dichloroacetate
$55
Products Details
Product Description
– Sodium dichloroacetate is a metabolic regulator in cancer cells’ mitochondria with anticancer activity. Sodium dichloroacetate inhibits PDHK, resulting in decreased lactic acid in the tumor microenvironment. Sodium dichloroacetate increases reactive oxygen species (ROS) generation and promotes cancer cell apoptosis. Sodium dichloroacetate also works as NKCC inhibitor[1].
Web ID
– HY-Y0445A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C2HCl2NaO2
References
– [1]StakiÅ¡aitis D, et al. The Importance of Gender-Related Anticancer Research on Mitochondrial Regulator Sodium Dichloroacetate in Preclinical Studies In Vivo. Cancers (Basel). 2019 Aug 20;11(8). pii: E1210.
CAS Number
– 2156-56-1
Molecular Weight
– 150.92
Compound Purity
– 98.0
SMILES
– O=C(O[Na])C(Cl)Cl
Clinical Information
– Phase 3
Research Area
– Cancer
Solubility
– H2O : 100 mg/mL (ultrasonic)
Target
– Apoptosis, NKCC, PDHK, Reactive Oxygen Species
Pathway
– Apoptosis, Immunology/Inflammation, Membrane Transporter/Ion Channel, Metabolic Enzyme/Protease, NF-κB
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
