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Products Details
Product Description
– SNIPER(ABL)-049, a compound that conjugates Imatinib (ABL inhibitor) with Bestatin (IAP ligand) through a linker, effectively reduces BCR-ABL protein levels, demonstrating a DC50 of 100 μM[1].
Web ID
– T18693
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C52H66N10O8
References
– Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.
Molecular Weight
– C52H66N10O8
SMILES
– CC1=CC=C(NC(C2=CC=C(CN3CCN(C(COCCOCCOCCNC([C@H](CC(C)C)NC([C@@H](O)[C@@H](CC4=CC=CC=C4)N)=O)=O)=O)CC3)C=C2)=O)C=C1NC5=NC=CC(C6=CC=CN=C6)=N5
Target
– Others
Pathway
– Others
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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