SMCC-DM1

$120$1,920

Products Details

Product Description

– SMCC-DM1 (DM1-SMCC) is a agent-linker conjugate composed of a potent microtubule-disrupting agent DM1 and a linker SMCC to make antibody agent conjugate (ADC)[1].

Web ID

– HY-101070

Storage Temperature

– -80°C, stored under nitrogen

Shipping

– Dry Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C51H66ClN5O16S

References

– [1]Shao S, et al. Site-specific and hydrophilic ADCs through disulfide-bridged linker and branched PEG. Bioorg Med Chem Lett. 2018 May 1;28(8):1363-1370.

CAS Number

– 1228105-51-8

Molecular Weight

– 1072.61

Compound Purity

– 98.87

SMILES

– O=C(O[C@H]([C@@]1(C)[C@H]([C@@H]([C@@]2([H])OC(N[C@]3(O)C2)=O)C)O1)CC(N(C)C4=CC(C/C(C)=C/C=C/[C@H]3OC)=CC(OC)=C4Cl)=O)[C@@H](N(C(CCSC(C5=O)CC(N5CC6CCC(C(ON7C(CCC7=O)=O)=O)CC6)=O)=O)C)C

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 16.67 mg/mL (ultrasonic;warming;heat to 80°C)

Target

– Drug-Linker Conjugates for ADC

Isoform

– Maytansinoids

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– ADC Related

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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