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Products Details
Product Description
– SJFδ is a 10-atom linker PROTAC that selectively degrades p38δ with a DC50 of 46.17 nM, without degrading p38α, p38β, or p38γ[1].
Web ID
– T18682
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C62H63F2N7O12S
References
– Smith BE, et al. Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase. Nat Commun. 2019 Jan 10;10(1):131.
CAS Number
– 2254609-23-7
Molecular Weight
– C62H63F2N7O12S
SMILES
– C(NC1=CC(F)=C(OC=2C3=C(C=C(OCCOCCOCCOC4=C(CNC(=O)[C@H]5N(C([C@H](C(C)C)N6CC=7C(C6=O)=CC=CC7)=O)C[C@H](O)C5)C=CC(=C4)C=8SC=NC8C)C(OC)=C3)N=CC2)C=C1)(=O)C9(C(NC%10=CC=C(F)C=C%10)=O)CC9
Target
– Antibacterial|||Tyrosine Kinases|||Influenza Virus|||HSP|||Antibiotic
Pathway
– Others
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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