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Products Details
Product Description
– SJ988497 is a PROTAC JAK2 degrader that effectively inhibits proliferation in CRLF2-rearranged (CRLF2r) cells and facilitates the degradation of the CRBN neosubstrate GSPT1. Composed of a Ruxolitinib derivative, a linker, and the CRBN ligand Pomalidomide, SJ988497 is utilized in researching acute lymphoblastic leukemia (ALL) [1].
Web ID
– T74994
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C36H36N10O5
CAS Number
– 2595365-41-4
Molecular Weight
– C36H36N10O5
SMILES
– O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCCCNC(=O)C4=CC=C(NC5=NC(=C6C(=N5)NC=C6)C7=CN(CCC)N=C7)C=C4
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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