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SI-109
Price range: 2,632 CAD through 8,160 CAD
Products Details
Product Description
– SI-109 is a potent inhibitor of STAT3 SH2 domain (Ki=9 nM),and with antitumor activity.
Web ID
– T12905
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C40H44F2N7O9P
References
– Bai L, et al. A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo. Cancer Cell. 2019 Nov 11;36(5):498-511.e17.
CAS Number
– 2429877-30-3
Molecular Weight
– C40H44F2N7O9P
SMILES
– O=C([C@@H](NC([C@@H]1CC[C@H](CCN(C(C)=O)C[C@@H]2NC(C3=CC(C=C(C(F)(P(O)(O)=O)F)C=C4)=C4N3)=O)N1C2=O)=O)CCC(N)=O)NC(C5=CC=CC=C5)C6=CC=CC=C6
Target
– Others
Pathway
– JAK/STAT signaling|||Stem Cells
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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