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Sarcosine
$30 – $50
Products Details
Product Description
– Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].
Web ID
– HY-101037
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C3H7NO2
References
– [1]Katarzyna Socała, et al. Effects of sarcosine, a glycine transporter type 1 inhibitor, in two mouse seizure models. Pharmacol Rep. Mar-Apr 2010;62(2):392-7.|[2]Mei-Yi Lee, et al. Effects of sarcosine and N, N-dimethylglycine on NMDA receptor-mediated excitatory field potentials. J Biomed Sci. 2017; 24: 18.
CAS Number
– 107-97-1
Molecular Weight
– 89.09
Compound Purity
– 98.0
SMILES
– O=C(O)CNC
Clinical Information
– Phase 4
Research Area
– Cancer
Solubility
– DMSO : < 1 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Target
– Endogenous Metabolite;GlyT
Isoform
– GlyT1;Human Endogenous Metabolite
Pathway
– Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
