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Products Details
Product Description
– [Sar9,Met(O2)11]-Substance P acetate is a tachykinin NK1 receptor selective agonist. [Sar9,Met(O2)11]-Substance P acetate is a selective tachykinin NK1 receptor agonist.[Sar9,Met(O2)11]-Substance P acetate and septide (10-100 pmol per rat, i.c.v.) are equipotent in increasing mean arterial blood pressure (MAP) and heart rate (HR), yet they have dissimilar time-course. Both agonists increase dose-dependently face washing and sniffing while [Sar9,Met(O2)11]-Substance P acetate is the sole to produce grooming.
Web ID
– TP1369L
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C66H106N18O18S
References
– Cellier E, et al. Characterization of central and peripheral effects of septide with the use of five tachykinin NK1 receptor antagonists in the rat. Br J Pharmacol. 1999 Jun;127(3):717-28.
Molecular Weight
– C66H106N18O18S
Compound Purity
– 1
SMILES
– O=C(N1CCC[C@H]1C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@@H](CC2=CC=CC=C2)C(N(CC(N[C@@H](CC(C)C)C(N[C@H](C(N)=O)CCS(C)(=O)=O)=O)=O)C)=O)=O)CC3=CC=CC=C3)=O)=O)CCC(N)=O)=O)[C@H](CCCCN)NC([C@H]4N(CCC4)C([C@H](CCCNC(N)=N)N)=O)=O.CC(O)=O.O
Pathway
– GPCR/G Protein|||Neuroscience
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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