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(S)-MCPG

$79$436

Products Details

Product Description

– (S)-MCPG ((+)-MCPG) is a potent group I/II metabotropic glutamate receptor (mGluRs) antagonist and the active isomer of (RS)-MCPG (HY-100371)[1]. (S)-MCPG can be used for the study of the function of mGluRs in spatial learning[2].

Web ID

– HY-100406

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C10H11NO4

References

– [1]Bernadett Boda, et al. Reversal of activity-mediated spine dynamics and learning impairment in a mouse model of Fragile X syndrome. Eur J Neurosci. 2014 Apr;39(7):1130-7.|[2]F Bordi, et al. Effects of the metabotropic glutamate receptor antagonist MCPG on spatial and context-specific learning. Neuropharmacology. 1996;35(11):1557-65.

CAS Number

– 150145-89-4

Molecular Weight

– 209.20

Compound Purity

– 99.61

SMILES

– OC(C1=CC=C([C@](C)(N)C(O)=O)C=C1)=O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 1M NaOH : 22 mg/mL (ultrasonic;adjust pH to 11 with NaOH)

Target

– mGluR

Isoform

– mGluR

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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