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(S)-Coriolic acid
Price range: 622 CAD through 2,320 CAD
Products Details
Product Description
– (S)-Coriolic acid (13(S)-HODE) is an important intracellular signaling agent generated by the reaction of linoleic acid with plant and mammalian lipoxygenases. It is involved in cell proliferation and differentiation in various biological systems and inhibits the adhesion of tumor cells to the vascular endothelium, while down-regulating IRGpIIb/IIIa receptor expression at around 1 μM. Additionally, (S)-Coriolic acid is a metabolite of 15-lipoxygenase (15-LOX) and often acts as an endogenous ligand to activate PPARγ. It induces mitochondrial dysfunction and airway epithelial damage.
Web ID
– T37974
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C18H32O3
References
– Mabalirajan U, et al. Linoleic acid metabolite drives severe asthma by causing airway epithelial injury. Sci Rep. 2013;3:1349.
CAS Number
– 29623-28-7
Molecular Weight
– C18H32O3
Compound Purity
– 0.9767
SMILES
– C(=C/C=CCCCCCCCC(O)=O)[C@H](CCCCC)O
Pathway
– DNA Damage/DNA Repair|||Metabolism
Product type
– Natural Product
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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