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Products Details
Product Description
– Rubratoxin A is a natural mycotoxin and competitive inhibitor of protein phosphatase 2A (PP2A) with an IC50 of 170 nM. Rubratoxin A causes suppression of tumor metastasis and reduction of primary tumor volume in mouse xenografts[1].
Web ID
– HY-126730
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H32O11
References
– [1]Wada S, et al. Rubratoxin A specifically and potently inhibits protein phosphatase 2A and suppresses cancer metastasis. Cancer Sci. 2010 Mar;101(3):743-50.
CAS Number
– 22467-31-8
Molecular Weight
– 520.53
SMILES
– O=C(C1=C2[C@H](O)[C@H]([C@H](O)CCCCCC)C3=C(C[C@H]([C@@H]([C@@H]4CC=CC(O4)=O)O)C1)C(O)OC3=O)OC2=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Phosphatase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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