Rosmarinic acid

SKU T2765-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 58 CAD through 942 CAD

Products Details

Product Description

– Rosmarinic acid (Labiatenic acid) is widely found in plants and has antioxidant, anti-inflammatory, and antibacterial activities. It inhibits MAO-A, MAO-B, and COMT with IC50 of 50.1, 184.6, and 26.7 μM respectively.

Web ID

– T2765

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C18H16O8

Citations

– 1. Jang S A, Hwang Y H, Yang H, et al. Water Extract of Mentha arvensis L. Attenuates Estrogen Deficiency-Induced Bone Loss by Inhibiting Osteoclast Differentiation. Frontiers in Pharmacology. 2021, 12. 2. Shim K S, Hwang Y H, Jang S A, et al.  Water Extract of Lysimachia christinae Inhibits Trabecular Bone Loss and Fat Accumulation in Ovariectomized Mice. Nutrients. 2020, 12(7): 1927 3. Zhang H, Liang B, Sang X, et al.Discovery of Potential Inhibitors of SARS-CoV-2 Main Protease by a Transfer Learning Method.Viruses.2023, 15(4): 891. 4. Quan W, Wang Y, Chen Y, et al.Screening of rosmarinic acid from Salvia miltiorrhizae acting on the novel target TRPC1 based on the ‘homology modelling–virtual screening–molecular docking–affinity assay–activity evaluation’method.Pharmaceutical Biology.2023, 61(1): 155-164. 5. Li X W, Yuan S C, Wang M, et al.Rosmarinic acid ameliorates autoimmune responses through suppression of intracellular nucleic acid-mediated type I interferon expression.Biochemical and Biophysical Research Communications.2023 6. Othman N M, Elhawary Y M, Elbeltagy M G, et al.The Effect of Rosmarinus Officinalis as a Potential Root Canal Medication on the Viability of Dental Pulp Stem Cells.The Journal of Contemporary Dental Practice.2023, 24(9): 623-631. 7. Structure-based identification of HNF4α agonists: Rosmarinic acid as a promising candidate for NAFLD treatment

References

– Andrade JM, et al. Combining in vitro and in silico approaches to evaluate the multifunctional profile of rosmarinic acid from Blechnum brasiliense on targets related to neurodegeneration. Chem Biol Interact. 2016 Jul 25;254:135-45.

CAS Number

– 20283-92-5

Molecular Weight

– C18H16O8

Compound Purity

– 0.9925

SMILES

– C([C@@H](OC(/C=C/C1=CC(O)=C(O)C=C1)=O)C(O)=O)C2=CC(O)=C(O)C=C2

Pathway

– Apoptosis|||NF-κB|||Metabolism|||Neuroscience

Product type

– Natural Product

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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