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Ropinirole (hydrochloride)
$66 – $132
Products Details
Product Description
– Ropinirole (SKF 101468) hydrochloride is an orally active, potent D3/D2 receptor agonist with a Ki of 29 nM for D2 receptor. Ropinirole hydrochloride has pEC50s of 7.4, 8.4 and 6.8 for hD2, hD3 and hD4 receptors, respectively. Ropinirole hydrochloride has no affinity for the D1 receptors. Ropinirole hydrochloride has the potential for Parkinson’s disease[1][2].
Web ID
– HY-B0623A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C16H25ClN2O
References
– [1]Eden, R.J., et al., Preclinical pharmacology of ropinirole (SK&F 101468-A) a novel dopamine D2 agonist. Pharmacol Biochem Behav, 1991. 38(1): p. 147-54.|[2]Mavrikaki M, et al. Ropinirole regulates emotionality and neuronal activity markers in the limbic forebrain. Int J Neuropsychopharmacol. 2014 Dec;17(12):1981-93.
CAS Number
– 91374-20-8
Molecular Weight
– 296.84
Compound Purity
– 99.85
SMILES
– O=C1NC2=C(C(CCN(CCC)CCC)=CC=C2)C1.Cl
Clinical Information
– Launched
Research Area
– Neurological Disease
Solubility
– DMSO : 16.67 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Target
– Dopamine Receptor
Isoform
– D2 Receptor;D3 Receptor;D4 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
