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Products Details
Product Description
– RMI 10874 is a tilorone analogue. Tilorone is a small-molecule, orally bioavailable antiviral agent. RMI 10874 completely abolishes lung colonization of an H-2 negative (GR9.B9) MCA-induced fibrosarcoma clone.
Web ID
– HY-100279
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C21H26N2O4
References
– [1]Algarra I, et al. Generation and control of metastasis in experimental tumor systems; inhibition of experimental metastases by a tilorone analogue. Int J Cancer. 1993 May 28;54(3):518-23.|[2]Algarra I, et al. Effect of in vivo activation of natural killer (NK) cells by a tilorone analogue on the survival of mice injected intravenously with different experimental murine tumours. Clin Exp Immunol. 1996 Mar;103(3):499-505.|[3]Ekins S, et al. Efficacy of Tilorone Dihydrochloride against Ebola Virus Infection. Antimicrob Agents Chemother. 2018 Jan 25;62(2). pii: e01711-17.
CAS Number
– 38020-45-0
Molecular Weight
– 370.44
SMILES
– O=C1C2=C(OC3=C1C=CC(OCCN(C)C)=C3)C=C(OCCN(C)C)C=C2
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
