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Rifabutin
$84 – $312
Products Details
Product Description
– Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.
Web ID
– HY-17025
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C46H62N4O11
References
– [1]Review Article: Rifabutin in the Treatment of Refractory Helicobacter pylori Infection
J. P. Gisbert, X. Calvet Issue Alimentary Pharmacology & Therapeutics Volume 35, Issue 2, pages 209-221, January 2012|[2]Vourvahis M, Davis J, Wang R, Layton G, Choo HW, Chong CL, Tawadrous M.
Effect of rifampin and rifabutin on the pharmacokinetics of lersivirine and effect of lersivirine on the pharmacokinetics of rifabutin and 25-o-desacetyl-rifabutin in healthy subjects.
Antimicrob Agents Chemother. 2012 Aug;56(8):4303-9.|[3]Gisbert JP, Castro-Fernandez M, Perez-Aisa A, Cosme A, Molina-Infante J, Rodrigo L, Modolell I, Cabriada JL, Gisbert JL, Lamas E, Marcos E, Calvet X.
Fourth-line rescue therapy with rifabutin in patients with three Helicobacter pylori eradication failures.
Aliment Pharmacol Ther. 2012 Apr;35(8):941-7. doi: 10.1111/j.1365-2036.2012.05053.x.|[4]Gisbert JP, Calvet X.
Review article: rifabutin in the treatment of refractory Helicobacter pylori infection.
Aliment Pharmacol Ther. 2012 Jan;35(2):209-21. doi: 10.1111/j.1365-2036.2011.04937.x.|[5]Horne DJ, Spitters C, Narita M.
Experience with rifabutin replacing rifampin in the treatment of tuberculosis.
Int J Tuberc Lung Dis. 2011 Nov;15(11):1485-9, i.
CAS Number
– 72559-06-9
Molecular Weight
– 847.00
Compound Purity
– 99.20
SMILES
– C[C@H]1/C=C/C=C(C)C(/N=C2C(O)=C3C(C4=C(O[C@@](O/C=C/[C@H](OC)[C@@H](C)[C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@H]1O)(C)C4=O)C(C)=C3O)=C5C/2=NC6(CCN(CC(C)C)CC6)N5)=O
Clinical Information
– Launched
Research Area
– Infection
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Antibiotic;Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
