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Products Details
Product Description
– RET-IN-10 is a potent inhibitor of RET. RET loss of function mutations leads to Hirschsprung’s disease, while its gain of function mutations is associated with a variety of human tumors. RET-IN-10 has the potential for the research of cancer diseases (extracted from patent WO2021135938A1, compound 18)[1].
Web ID
– HY-143615
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C29H28N8OS
References
– [1]Anhu Li. Heterocyclic sulfoximine compounds and intermediates thereof, methods of preparation and applications. Patent WO2021135938A1.
CAS Number
– 2662622-44-6
Molecular Weight
– 536.65
SMILES
– N#CC1=C2C(C3=CN=C(N4CCC(CC4)N=[S@](C5=CC=CC=C5)(C)=O)C=C3)=CC(C6=CN(C)N=C6)=CN2N=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– RET
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
