Rebamipide

SKU T1562-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 72 CAD through 245 CAD

Products Details

Product Description

– Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis in the gastric mucosa. This agent also inhibits H. pylori-induced production of tumor necrosis factor (TNF) alpha and subsequent inflammation of the gastric mucosa. In addition, rebamipide scavenges oxygen-derived free radicals that potentially cause mucosal injury, and stimulates prostaglandin EP4 receptor gene expression followed by mucous secretion, thereby enhancing the gastric mucosal defense.

Web ID

– T1562

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H15ClN2O4

References

– Matsuda T, et al. Drugs R D. 2003;4(1):19-28.

CAS Number

– 90098-04-7

Molecular Weight

– C19H15ClN2O4

Compound Purity

– 0.999

SMILES

– OC(=O)C(CC1=CC(=O)NC2=C1C=CC=C2)NC(=O)C1=CC=C(Cl)C=C1

Target

– Others

Pathway

– Immunology/Inflammation|||GPCR/G Protein|||Neuroscience|||Oxidation-Reduction

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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