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(-)-Rasfonin
SKU
HY-121532-500μg
Category Natural Products
Tags Apoptosis;Autophagy;GPCR/G Protein, Apoptosis;Autophagy;Ras, Cancer
$370
Only 1000 item(s) left in stock.
Products Details
Product Description
– (-)-Rasfonin is a fungal secondary metabolite and inhibits small G proteins Ras. (-)-Rasfonin induces apoptosis, necrosis and autophagy in ACHN cells (a renal carcinoma cell line)[1].
Web ID
– HY-121532
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C25H38O6
References
– [1]Hou B, et al. Different Role of Raptor and Rictor in Regulating Rasfonin-Induced Autophagy and Apoptosis in Renal Carcinoma Cells. Chem Biodivers. 2020;17(12):e2000743.
CAS Number
– 303156-68-5
Molecular Weight
– 434.57
SMILES
– O=C(O[C@H](C=C1)[C@@H]([C@@H](C)C[C@@H](C)C/C(C)=C/C)OC1=O)/C=C/C(C)=C/[C@@H](CO)CCO
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Autophagy;Ras
Pathway
– Apoptosis;Autophagy;GPCR/G Protein
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.