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Raleukin
$350 – $1,650
Products Details
Product Description
– Raleukin (AMG-719) is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist. Raleukin (AMG-719) is the first biological agent to block the pro-inflammatory effects[1][2].
Web ID
– HY-108841
Storage Temperature
– Store at 4°C for 2 years, do not freeze
Shipping
– Isolate blue ice and the product with bubble pack to avoid direct contact
Applications
– Cancer-programmed cell death
Molecular Formula
– C759H1186N208O232S10
References
– [1]Cvetkovic RS, et al. Anakinra. BioDrugs. 2002;16(4):303-11; discussion 313-4.|[2]McCall M, et al. Anakinra potentiates the protective effects of etanercept in transplantation of marginal mass human islets in immunodeficient mice. Am J Transplant. 2012 Feb;12(2):322-9.|[3]Harnack U, et al. IL-1 receptor antagonist anakinra enhances tumour growth inhibition in mice receiving peptide vaccination and beta-(1-3),(1-6)-D-glucan. Anticancer Res. 2010 Oct;30(10):3959-65.
CAS Number
– 143090-92-0
Molecular Weight
– 17257.60
Compound Purity
– 99.40
SMILES
– [Anakinra]
Clinical Information
– Launched
Research Area
– Cancer; Inflammation/Immunology
Solubility
– H2O
Target
– Interleukin Related
Isoform
– IL-1
Pathway
– Immunology/Inflammation
Product type
– Inhibitory Antibodies
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
