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Rafoxanide
$65 – $102
Products Details
Product Description
– Rafoxanide is a poent, orally active halogenated salicylaniline agent with antiparasitic activity. Rafoxanide can be used for the control of infestation with Hemonchus species and Fasciola species in sheep and cattle and Estrus ovis in sheep. Rafoxanide interferes with energy metabolism in trematodes by uncoupling oxidative phosphorylation. Rafoxanide eliminates 91-99% of the mature flukes and 50-90% of the younger flukes in ruminants[1][2][3].
Web ID
– HY-17598
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H11Cl2I2NO3
References
– [1]Rafoxanide|[2]El-Banna HA, et, al. Comparative pharmacokinetics of ivermectin alone and a novel formulation of ivermectin and rafoxanide in calves and sheep. Parasitol Res. 2008 May;102(6):1337-42.|[3]van Wyk JA, et, al. Two field strains of Haemonchus contortus resistant to rafoxanide. Onderstepoort J Vet Res. 1987 Jun;54(2):143-6.
CAS Number
– 22662-39-1
Molecular Weight
– 626.01
Compound Purity
– 98.88
SMILES
– O=C(NC1=CC=C(OC2=CC=C(Cl)C=C2)C(Cl)=C1)C3=CC(I)=CC(I)=C3O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– DMSO : ≥ 31 mg/mL
Target
– Parasite
Pathway
– Anti-infection
Product type
– Reference compound
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