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Product Description
– Rachelmycin (CC-1065) is an antitumor antibiotic and a DNA-alkylating agent. Rachelmycin has cytotoxic potency that can be used as a cytotoxin to synthesis ADC. Rachelmycin effectively inhibits DNA synthesis. Rachelmycin can be used for cancer and infection research[1][2][3].
Web ID
– HY-12457
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C37H33N7O8
References
– [1]W C Krueger, et al. Calf Thymus DNA binding/bonding Properties of CC-1065 and Analogs as Related to Their Biological Activities and Toxicities. Chem Biol Interact. 1992 Mar;82(1):31-46.|[2]Martin DG, et al. CC-1065 (NSC 298223), a potent new antitumor agent improved production and isolation, characterization and antitumor activity. J Antibiot (Tokyo). 1981 Sep;34(9):1119-25.|[3]Reynolds VL, et al. The chemistry, mechanism of action and biological properties of CC-1065, a potent antitumor antibiotic. J Antibiot (Tokyo). 1986 Mar;39(3):319-34.
CAS Number
– 69866-21-3
Molecular Weight
– 703.70
SMILES
– O=C(N1C2=C(O)C(OC)=C3NC(C(N4C5=C(O)C(OC)=C6NC(C(N7C[C@](C8)([H])[C@]98C%10=C(NC=C%10C)C(C=C79)=O)=O)=CC6=C5CC4)=O)=CC3=C2CC1)N
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;DNA/RNA Synthesis
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
