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Products Details
Product Description
– R1-11 is an indole ICMT inhibitor with an IC50 of 0.6 μM and has anticancer activity. R1-11 inhibits MDA-MB231 and PC3 cells with IC50s of 2.2 μM and 2.0 μM, respectively[1].
Web ID
– HY-149715
Shipping
– Room temperature
Molecular Formula
– C25H37N5
References
– [1]Yang WS et al. Isoprenyl carboxyl methyltransferase inhibitors: a brief review including recent patents. Amino Acids. 2017 Sep;49(9):1469-1485.
Molecular Weight
– 407.59
SMILES
– CCCCCCCCN1C(CN(CC)CC)=CC2=CC(C3=CN=C(N)N=C3)=CC=C12
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– ICMT
Pathway
– GPCR/G Protein
Product type
– Reference compound
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