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(R)-ZG197
Products Details
Product Description
– (R)-ZG197 is a highly selective Staphylococcus aureus Caseinolytic protease P (SaClpP) activator with an EC50 of 1.5 μM. (R)-ZG197 also activates Homo sapiens ClpP (HsClpP) with an EC50 of 31.4 μM[1].
Web ID
– HY-152096
Shipping
– Room temperature
Molecular Formula
– C28H35F3N4O3
References
– [1]Wei B, et al. Anti-infective therapy using species-specific activators of Staphylococcus aureus ClpP. Nat Commun. 2022 Nov 14;13(1):6909.
Molecular Weight
– 532.60
SMILES
– O=C(N1CCC(N([C@H]2[C@@H](C)CC)[C@]1([H])CN([C@H](C)C3=C(C=CC=C4)C4=CC=C3)C2=O)=O)NCCCC(F)(F)F
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.