Download Files:
(R)-Baclofen
$41 – $238
Products Details
Product Description
– (R)-Baclofen (Arbaclofen) is a selective GABAB receptor agonist[1].
Web ID
– HY-17354
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C10H12ClNO2
References
– [1]Falch E, et al. Comparative stereostructure-activity studies on GABAA and GABAB receptor sites and GABA uptake using rat brain membrane preparations. J Neurochem. 1986 Sep;47(3):898-903.|[2]Falch E, et al. Comparative stereostructure-activity studies on GABAA and GABAB receptor sites and GABA uptake using rat brain membrane preparations. J Neurochem. 1986 Sep;47(3):898-903.|[3]Orsnes G, et al. The effect of baclofen on the transmission in spinal pathways in spastic multiple sclerosis patients. Clin Neurophysiol. 2000 Aug;111(8):1372-9.|[4]Hong YG, et al. Effects of phaclofen and the enantiomers of baclofen on cardiovascular responses to intrathecal administration of L- and D-baclofen in the rat. Eur J Pharmacol. 1991 Apr 24;196(3):267-75.
CAS Number
– 69308-37-8
Molecular Weight
– 213.66
Compound Purity
– 99.49
SMILES
– ClC1=CC=C([C@](CC(O)=O)([H])CN)C=C1
Clinical Information
– Launched
Research Area
– Neurological Disease
Solubility
– DMSO : 1 mg/mL (ultrasonic;warming;heat to 80°C)|H2O : 5 mg/mL (ultrasonic)
Target
– GABA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
