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(R)-(+)-Aminoglutethimide

$114$182

Products Details

Product Description

– (R)-(+)-Aminoglutethimide is a potent and orally active aromatase inhibitor. (R)-(+)-Aminoglutethimide has the potential for the research of breast cancer[1].

Web ID

– HY-W392925

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C13H16N2O2

References

– [1]Dai Sig Im, et al. Chemo-enzymatic synthesis of (R)-(+)-aminoglutethimide by kinetic resolution of (±)-4-cyano-4-phenyl-1-hexanol. Journal of Molecular Catalysis B: Enzymatic. 2003, 26:185–191.|[2]Egger H, Bartlett F, Itterly W, Rodebaugh R, Shimanskas C. Metabolism of aminoglutethimide in the rat. Drug Metab Dispos. 1982 Jul-Aug;10(4):405-12.

CAS Number

– 55511-44-9

Molecular Weight

– 232.28

SMILES

– O=C([C@@](CC)(C1=CC=C(N)C=C1)CC2)NC2=O

Clinical Information

– Launched

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Cytochrome P450

Isoform

– CYP19

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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