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(R)-(+)-Aminoglutethimide
SKU
HY-W392925-100mg
Category Reference compound
Tags Cancer, Cytochrome P450, Metabolic Enzyme/Protease
$114 – $182
Products Details
Product Description
– (R)-(+)-Aminoglutethimide is a potent and orally active aromatase inhibitor. (R)-(+)-Aminoglutethimide has the potential for the research of breast cancer[1].
Web ID
– HY-W392925
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C13H16N2O2
References
– [1]Dai Sig Im, et al. Chemo-enzymatic synthesis of (R)-(+)-aminoglutethimide by kinetic resolution of (±)-4-cyano-4-phenyl-1-hexanol. Journal of Molecular Catalysis B: Enzymatic. 2003, 26:185–191.|[2]Egger H, Bartlett F, Itterly W, Rodebaugh R, Shimanskas C. Metabolism of aminoglutethimide in the rat. Drug Metab Dispos. 1982 Jul-Aug;10(4):405-12.
CAS Number
– 55511-44-9
Molecular Weight
– 232.28
SMILES
– O=C([C@@](CC)(C1=CC=C(N)C=C1)CC2)NC2=O
Clinical Information
– Launched
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Cytochrome P450
Isoform
– CYP19
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.