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Products Details
Product Description
– QCA570 is an effective BET degrader based on PROTAC (IC50: 10 nM for BRD4 BD1 Protein).
Web ID
– T16701
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C39H33N7O4S
References
– Qin C, et al. Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression. J Med Chem. 2018 Aug 9;61(15):6685-6704.
CAS Number
– 2207569-08-0
Molecular Weight
– C39H33N7O4S
SMILES
– C(C=1C2=C(N3C(=NN=C3C)COC2)SC1C#CC4=CN(CCCC#CC5=C6C(C(=O)N(C6)C7C(=O)NC(=O)CC7)=CC=C5)N=C4)C8=CC=CC=C8
Target
– TRP/TRPV Channel|||COX|||Endogenous Metabolite
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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