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Pulegone
SKU
HY-N1500-10mM/1mL
Category Natural Products
Tags Endogenous Metabolite;TRP Channel, Inflammation/Immunology, Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
$50 – $55
Products Details
Product Description
– Pulegone, the major chemical constituent of Nepeta catariaessential oil which is an aromatic herb, is one of avian repellents[1]. The molecular target for the repellent action of Pulegone in avian species is nociceptive TRP ankyrin 1 (TRPA1). Pulegone stimulates both TRPM8 and TRPA1 channel in chicken sensory neurons and suppresses the former but not the latter at high concentrations[2].
Web ID
– HY-N1500
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C10H16O
References
– [1]Božović M, et al. <i>Calamintha nepeta</i> (L.) Savi and its Main Essential Oil Constituent Pulegone: Biological Activities and Chemistry. Molecules. 2017 Feb 14;22(2).|[2]Majikina A, et al. Involvement of nociceptive transient receptor potential channels in repellent action of pulegone. Biochem Pharmacol. 2018 May;151:89-95.
CAS Number
– 89-82-7
Molecular Weight
– 152.23
Compound Purity
– 98.80
SMILES
– O=C1/C(CC[C@@H](C)C1)=C(C)/C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : ≥ 270 mg/mL
Target
– Endogenous Metabolite;TRP Channel
Pathway
– Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease;Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.