Download Files:
PRT062607 (Hydrochloride)
$156 – $634
Products Details
Product Description
– PRT062607 Hydrochloride (P505-15 Hydrochloride) is a highly specific and potent inhibitor of purified Syk (IC50 1-2 nM).
Web ID
– HY-15323
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C19H24ClN9O
Citations
– Harvard Medical School LINCS LIBRARY|Int J Ophthalmol. 2022 Jul 18;15(7):1044-1052.|Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2207280119.
References
– [1]Coffey G, et al. Specific inhibition of spleen tyrosine kinase suppresses leukocyte immune function and inflammation in animal models of rheumatoid arthritis. J Pharmacol Exp Ther. 2012 Feb;340(2):350-9.
CAS Number
– 1370261-97-4
Molecular Weight
– 429.91
Compound Purity
– 98.68
SMILES
– NC(C1=CN=C(N[C@H]2[C@@H](N)CCCC2)N=C1NC3=CC=CC(N4N=CC=N4)=C3)=O.[H]Cl
Clinical Information
– Phase 2
Research Area
– Cancer
Solubility
– DMSO : ≥ 33 mg/mL|H2O : ≥ 50 mg/mL
Target
– Syk
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
