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Products Details
Product Description
– PROTAC TTK Degrader-2 is a potent threonine tyrosine kinase (TTK) PROTAC degrader, achieving DC50 values of 3.1 nM in COLO-205 cells and 12.4 nM in HCT-116 cells. It demonstrates effective target degradation and anticancer activity in a COLO-205 human colorectal cancer cell xenograft mouse model [1].
Web ID
– T81374
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C49H57N9O7
CAS Number
– 2953426-48-5
Molecular Weight
– C49H57N9O7
SMILES
– O=C1N(C=2C(=CN=C(NC3=C(OC)C=C(C=C3)N4CCN(C(CCCCCC#CC=5C=C6C(=CC5)CN(C6=O)C7C(=O)NC(=O)CC7)=O)CC4)N2)C(C)=C1)[C@H]8CC[C@@H](NC(CC)=O)CC8
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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