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Products Details
Product Description
– PROTAC CDK2/9 Degrader-1 is a potent CDK2 and CDK9 dual degrader(DC50 of 62 nM and 33 nM).
Web ID
– T12552
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C40H41N13O7
References
– Zhou F, et al. Development of selective mono or dual PROTAC degrader probe of CDK isoforms. Eur J Med Chem. 2019 Dec 6;187:111952.
CAS Number
– 2408641-24-5
Molecular Weight
– C40H41N13O7
SMILES
– O=C(NC1=CC=C(C=C1)CN2CCN(C(=O)CCC(=O)NCCNC3=CC=CC=4C(=O)N(C(=O)C34)C5C(=O)NC(=O)CC5)CC2)C6=NNC=C6NC=7N=CN=C8NC=CC87
Target
– Apoptosis|||AMPK|||Autophagy
Pathway
– Cell Cycle/Checkpoint|||PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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