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Proflavine (hemisulfate)
$60 – $66
Products Details
Product Description
– Proflavine hemisulfate, an acridine dye, is a known DNA intercalating agent. Anti-microbial agent[1]. Proflavine hemisulfate behaves as a pore blocker for Kir3.2. Proflavine hemisulfate is a potential lead compound for Kir3.2-associated neurological diseases[2].
Web ID
– HY-B0883
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C13H11N3.1/2H2SO4
References
– [1]Hitoshi Kawada, et al. Isolation of proflavine as a blocker of G protein-gated inward rectifier potassium channels by a cell growth-based screening system. Neuropharmacology. 2016 Oct;109:18-28.|[2]Mansour K.Gatasheh, et al. Proflavine an acridine DNA intercalating agent and strong antimicrobial possessing potential properties of carcinogen. Karbala International Journal of Modern Science. 2017 Dec, 3(4): 272-278.|[3]Jiaxin Chen, et al. Determination of proflavine in rat whole blood without sample pretreatment by laser desorption postionization mass spectrometry. Anal Bioanal Chem. 2017 Apr;409(11):2813-2819.
CAS Number
– 1811-28-5
Molecular Weight
– 258.28
Compound Purity
– 98.45
SMILES
– NC1=CC2=NC3=CC(N)=CC=C3C=C2C=C1.[0.5H2SO4]
Clinical Information
– Launched
Research Area
– Infection; Cancer
Solubility
– H2O : ≥ 5 mg/mL
Target
– Autophagy;Bacterial;Potassium Channel
Pathway
– Anti-infection;Autophagy;Membrane Transporter/Ion Channel
Product type
– Dye Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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