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Product Description
– Proflavine, an acridine dye, is a known DNA intercalating agent. Anti-microbial agent[1]. Proflavine behaves as a pore blocker for Kir3.2. Proflavine is a potential lead compound for Kir3.2-associated neurological diseases[2].
Web ID
– HY-B1741
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C13H11N3
References
– [1]Mansour K.Gatasheh, et al. Proflavine an acridine DNA intercalating agent and strong antimicrobial possessing potential properties of carcinogen. Karbala International Journal of Modern Science. 2017 Dec, 3(4): 272-278. |[2]Hitoshi Kawada, et al. Isolation of proflavine as a blocker of G protein-gated inward rectifier potassium channels by a cell growth-based screening system. Neuropharmacology. 2016 Oct;109:18-28. |[3]Jiaxin Chen, et al. Determination of proflavine in rat whole blood without sample pretreatment by laser desorption postionization mass spectrometry. Anal Bioanal Chem. 2017 Apr;409(11):2813-2819.
CAS Number
– 92-62-6
Molecular Weight
– 209.25
SMILES
– NC1=CC2=NC3=CC(N)=CC=C3C=C2C=C1
Clinical Information
– Launched
Research Area
– Neurological Disease; Cancer
Solubility
– 10 mM in DMSO
Target
– Bacterial;Fluorescent Dye
Pathway
– Anti-infection;Others
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
