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Pranoprofen
$35 – $119
Products Details
Product Description
– Pranoprofen is a non-steroidal anti-inflammatory agent (NSAID) for the research of keratitis or other ophthalmology diseases. Pranoprofen inhibit COX-1 and COX-2 enzymes, thus blocking arachidonic acid converted to eicosanoids and reducing prostaglandins synthesis[1][2].
Web ID
– HY-B0336
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C15H13NO3
References
– [1]Toru Hosoi, et al. Effect of pranoprofen on endoplasmic reticulum stress in the primary cultured glial cells. Neurochem Int. 2009 Jan;54(1):1-6.|[2]Minting Chen, et al. The Therapeutic Effects and Possible Mechanism of Pranoprofen in Mouse Model of Corneal Alkali Burns. J Ophthalmol. 2020 Apr 6;2020:7485912.|[3]Xiaoli Wu,et al. Rescuing Dicer expression in inflamed colon tissues alleviates colitis and prevents colitis-associated tumorigenesis. Theranostics. 2020 Apr 27;10(13):5749-5762.
CAS Number
– 52549-17-4
Molecular Weight
– 255.27
Compound Purity
– 99.37
SMILES
– CC(C(O)=O)C1=CC2=C(C=C1)OC3=NC=CC=C3C2
Clinical Information
– Launched
Research Area
– Cancer; Inflammation/Immunology
Solubility
– DMSO : ≥ 100 mg/mL
Target
– Apoptosis;COX;PGE synthase
Isoform
– COX-1;COX-2
Pathway
– Apoptosis;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
