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Products Details
Product Description
– Pomalidomide-PEG2-Tos is an E3 ligase ligand-linker conjugates, composed of a cereblon ligand and two-unit PEG linker[1].
Web ID
– HY-130295
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H25N3O8S
References
– [1]Su S, et al. Potent and Preferential Degradation of CDK6 via Proteolysis Targeting Chimera Degraders. J Med Chem. 2019 Aug 22;62(16):7575-7582.
CAS Number
– 2599846-07-6
Molecular Weight
– 515.54
SMILES
– O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOS(C4=CC=C(C=C4)C)(=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– E3 Ligase Ligand-Linker Conjugates
Isoform
– Cereblon
Pathway
– PROTAC
Product type
– Reference compound
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