PMSF
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PMSF

SKU T0789-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 53 CAD through 88 CAD

Products Details

Product Description

– Phenylmethanesulfonyl fluoride (PMSF (Phenylmethylsulfonyl fluoride)) is an enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acid synthetase complex.

Web ID

– T0789

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C7H7FO2S

Citations

– 1. Xu G, Li T, Chen J, et al. Autosomal dominant retinitis pigmentosa-associated gene PRPF8 is essential for hypoxia-induced mitophagy through regulating ULK1mRNA splicing. Autophagy. 2018, 14(10): 1818-1830 2. Li X, Zhang H, Qiao S, et al Melatonin administration alleviates 2,2,4,4-tetra-brominated diphenyl ether (PBDE-47)-induced necroptosis and secretion of inflammatory factors via miR-140-5p/TLR4/NF-κB axis in fish kidney cells. Fish & Shellfish Immunology. 2022 3. Wen Q L, Yi H Q, Yang K, et al. Role of oncogene PIM-1 in the development and progression of papillary thyroid carcinoma: involvement of oxidative stress. Molecular and Cellular Endocrinology. 2021 Mar 1;523:111144. doi: 10.1016/j.mce.2020.111144 4. Song N, Guan X, Zhang S, et al.Discovery of a pyrrole-pyridinimidazole derivative as novel SIRT6 inhibitor for sensitizing pancreatic cancer to gemcitabine.Cell Death & Disease.2023, 14(8): 499. 5. Yan Y, Yu L, Chen B, et al.Mastoparan M Suppressed NLRP3 Inflammasome Activation by Inhibiting MAPK/NF-κB and Oxidative Stress in Gouty Arthritis.Journal of Inflammation Research.2023: 6179-6193. 6. Zeng X, Xu J, Liu J, et al.DYRK4 upregulates antiviral innate immunity by promoting IRF3 activation.EMBO reports.2024: 1-30. 7. Cutaneous wound healing functions of novel milk-derived antimicrobial peptides, hLFT-68 and hLFT-309 from human lactotransferrin, and bLGB-111 from bovine β-lactoglobulin

References

– Turini P, et al. J Pharmacol Exp Ther, 1969, 167(1), 98-104.

CAS Number

– 329-98-6

Molecular Weight

– C7H7FO2S

Compound Purity

– 0.999

SMILES

– FS(=O)(=O)Cc1ccccc1

Target

– Adenosine Receptor

Pathway

– Proteases/Proteasome

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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