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Products Details
Product Description
– PLK1/p38γ-IN-1(compound 14) is a multitarget inhibitors ofPLK1andp38γ. PLK1/p38γ-IN-1inhibits the growth of human hepatocellular carcinoma and hepatoblastoma cells in vitro[1].
Web ID
– HY-155377
Shipping
– Room temperature
Molecular Formula
– C21H26ClN3O2
References
– [1]Cheng Z, et al. Chee Wezen X. Combination of QSAR Modeling and Hybrid-Based Consensus Scoring to Identify Dual-Targeting Inhibitors of PLK1 and p38γ. J Chem Inf Model. 2023;63(21):6912-6924.
CAS Number
– 2418614-81-8
Molecular Weight
– 387.90
SMILES
– CCN(N=C1)C=C1[C@H]2[C@H](C(N3C4=CC=C(Cl)C=C4CCCC3)=O)CCCO2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– p38 MAPK;Polo-like Kinase (PLK)
Pathway
– Cell Cycle/DNA Damage;MAPK/ERK Pathway
Product type
– Reference compound
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