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Pilocarpine (nitrate)
$30 – $50
Products Details
Product Description
– Pilocarpine nitrate is a potent M3-type muscarinic acetylcholine receptor (M3 muscarinic receptor) agonist.
Web ID
– HY-B1006
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C11H17N3O5
References
– [1]Matsuzaki K, et al. Daily voluntary exercise enhances pilocarpine-induced saliva secretion and aquaporin 1 expression in rat submandibular glands. FEBS Open Bio. 2017 Dec 7;8(1):85-93.|[2]Yuan XL, et al. Cytotoxicity of pilocarpine to human corneal stromal cells and its underlying cytotoxic mechanisms. Int J Ophthalmol. 2016 Apr 18;9(4):505-11.|[3]Tonta MA, et al. Pilocarpine-induced relaxation of rat tail artery by a non-cholinergic mechanism and in the absence of an intact endothelium. Br J Pharmacol. 1994 Jun;112(2):525-32.
CAS Number
– 148-72-1
Molecular Weight
– 271.27
Compound Purity
– 99.83
SMILES
– [O-][N+](O)=O.O=C1OC[C@H](CC2=CN=CN2C)[C@@H]1CC
Clinical Information
– Launched
Research Area
– Neurological Disease; Cancer
Solubility
– DMSO : 250 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Target
– mAChR
Isoform
– mAChR3
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
