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Phenoxybenzamine hydrochloride
Price range: 46 CAD through 67 CAD
Products Details
Product Description
– Phenoxybenzamine hydrochloride (NCI-c01661) is the hydrochloride salt form of phenoxybenzamine, a synthetic, dibenzamine alpha-adrenergic antagonist with antihypertensive and vasodilatory properties. Phenoxybenzamine non-selectively and irreversibly blocks the postsynaptic alpha-adrenergic receptor in smooth muscle, thereby preventing vasoconstriction, relieving vasospasms, and decreasing peripheral resistance. Reflex tachycardia may occur and may be enhanced by blockade of alpha-2 receptors which enhances norepinephrine release. Phenoxybenzamine is reasonably anticipated to be a human carcinogen.
Web ID
– T1158
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C18H23Cl2NO
References
– Lenox, R.H., et al, Alpha 2-adrenergic receptor-mediated regulation of adenylate cyclase in the intact human platelet. Evidence for a receptor reserve. Mol Pharmacol, 1985. 27(1): p. 1-9.
CAS Number
– 63-92-3
Molecular Weight
– C18H23Cl2NO
Compound Purity
– 0.9804
SMILES
– Cl.CC(COc1ccccc1)N(CCCl)Cc1ccccc1
Target
– Others
Pathway
– GPCR/G Protein|||Neuroscience
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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