Download Files:
Products Details
Product Description
– Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC50s of 65±6 and 50±10 nM, respectively.
Web ID
– HY-15594
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C34H26N6O2
Citations
– J Phys Chem B. 2023 Jun 25.|Patent. US20210188889A1.|Cell Death Dis. 2021 Oct 25;12(11):999.|iScience. 9 October 2022, 105312.
References
– [1]Bharti SK, et al. Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability. J Biol Chem. 2013 Sep 27; 288(39):28217-29.
CAS Number
– 942936-75-6
Molecular Weight
– 550.61
SMILES
– C[N+]1=C2C=CC=CC2=CC(NC(C3=CC=C4C=CC5=CC=C(C(NC6=C[N+](C)=C7C=CC=CC7=C6)=O)N=C5C4=N3)=O)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 34 mg/mL
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
