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PDK1-IN-RS2
293 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– PDK1-IN-RS2 inhibits the activation of the downstream kinases S6K1 by PDK1. PDK1-IN-RS2 is a mimic of the peptide docking motif (PIFtide) and is a substrate-selective PDK1 inhibitor (Kd: 9 μM).
Web ID
– T16450
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C15H9ClN2O2S3
References
– Rettenmaier TJ, et al. A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18590-5.
CAS Number
– 1643958-89-7
Molecular Weight
– C15H9ClN2O2S3
SMILES
– Clc1ccc2nc(NS(=O)(=O)c3cc4ccccc4s3)sc2c1
Target
– Apoptosis
Pathway
– PI3K/Akt/mTOR signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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