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Products Details
Product Description
– PDdEC-NB is a disulfide cleavable linker used for the antibody-drug conjugate (ADC).
Web ID
– HY-126519
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C16H16N2O5S2
References
– [1]Flygare, John, et al. Anthracycline disulfide intermediates, antibody-​drug conjugates and methods.WO 2016040825 A1 20160317.
CAS Number
– 1956318-90-3
Molecular Weight
– 380.44
Compound Purity
– 97.63
SMILES
– O=C(OC1=CC=C([N+]([O-])=O)C=C1)OCC(SSC2=NC=CC=C2)(C)C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker
Isoform
– Cleavable Linker;Disulfide Cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
