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Products Details
Product Description
– PD25 is an AChE and BuChE inhibitor (hAChE IC50: 1.58 μM; eeAChE IC50: 1.63 μM; eqBuChE IC50: 2.39 μM). PD25 also has antioxidant activity, and inhibits DPPH (IC50: 29.55 μM). PD25 can be used for research of Alzheimer’s disease[1].
Web ID
– HY-155622
Shipping
– Room temperature
Molecular Formula
– C25H24N2O4
References
– [1]Bhanukiran K, et al. Discovery of Multitarget-Directed Ligands from Piperidine Alkaloid Piperine as a Cap Group for the Management of Alzheimer’s Disease. ACS Chem Neurosci. 2023 Aug 2;14(15):2743-2760.
Molecular Weight
– 416.47
SMILES
– O=C(N1CCN(C(/C=C/C2=CC=CC=C2)=O)CC1)/C=C/C=C/C3=CC=C(OCO4)C4=C3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Cholinesterase (ChE)
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
