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Products Details
Product Description
– PARP1-IN-6 is a dual tubulin/PARP-1 inhibitor with IC50 values of 0.94 and 0.48 μM, respectively.
Web ID
– HY-139879
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C16H11FN2O
References
– [1]Zheng L, et al. Discovery of a Dual Tubulin and Poly(ADP-Ribose) Polymerase-1 Inhibitor by Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, and Biological Evaluation. J Med Chem. 2021 Nov 11;64(21):15702-15715.
CAS Number
– 1654735-36-0
Molecular Weight
– 266.27
SMILES
– O=C1C2=CC=CC=C2N=C(/C=C/C3=CC(F)=CC=C3)N1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– PARP
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
