Osthole
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Osthole

SKU T2848-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 237 CAD

Products Details

Product Description

– Osthole (Osthol), a potential inhibitor of histamine H1 receptor, has been shown to stimulate osteoblast proliferation and differentiation.

Web ID

– T2848

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H16O3

Citations

– 1. Geng W, Guo X, Zhang L, et al. Resveratrol inhibits proliferation, migration and invasion of multiple myeloma cells via NEAT1-mediated Wnt/β-catenin signaling pathway Resveratrol inhibits proliferation, migration and invasion of multiple myeloma cells via NEAT1-mediated Wnt/β-catenin signaling pathway. Biomedicine & Pharmacotherapy. 2018 Nov;107:484-494. 2. Qu Y, Sun X, Wei N, et al.Inhibition of cutaneous heat‐sensitive Ca2+‐permeable transient receptor potential vanilloid 3 channels alleviates UVB‐induced skin lesions in mice.The FASEB Journal.2023, 37(12): e23309. 3. Xu Y, Qu Y, Zhang C, et al.Selective inhibition of overactive warmth-sensitive Ca2+-permeable TRPV3 channels by antispasmodic agent flopropione for alleviation of skin inflammation.Journal of Biological Chemistry.2023: 105595. 4. Li S H, Li M Y, Yuan T T, et al.Osthole Activates the Cholinergic Anti‐Inflammatory Pathway via α7nAChR Upregulation to Alleviate Inflammatory Responses.Chemistry & Biodiversity.2024: e202400290. 5. Yu X, Jiang J, Li C, et al.Osthole ameliorates wear particle-induced osteogenic impairment by mitigating endoplasmic reticulum stress via PERK signaling cascade.Molecular Medicine.2024, 30: 266.

References

– Ko FN, et al. Thromb Haemost, 1989, 62(3), 1996-1999.

CAS Number

– 484-12-8

Molecular Weight

– C15H16O3

Compound Purity

– 0.9996

SMILES

– COC1=C(CC=C(/C)C)C2=C(C=CC(=O)O2)C=C1

Pathway

– Neuroscience|||Apoptosis|||GPCR/G Protein|||Microbiology/Virology|||Immunology/Inflammation

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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