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48 CAD – 88 CADPrice range: 48 CAD through 88 CAD
Products Details
Product Description
– Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).
Web ID
– T10433
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C30H41N7O8S2
References
– Cross DA, et al. AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer. Cancer Discov. 2014 Sep;4(9):1046-61.
CAS Number
– 2070014-82-1
Molecular Weight
– C30H41N7O8S2
SMILES
– CS(O)(=O)=O.CS(O)(=O)=O.COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1nccc(n1)-c1cn(C)c2ccccc12
Target
– Others
Pathway
– Angiogenesis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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