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Oseltamivir
$30 – $50
Products Details
Product Description
– Oseltamivir (GS 4104) is an orally active influenza virus neuraminidase inhibitor (NAI). Oseltamivir inhibits influenza A/H3N2, A/H1N2, A/H1N1, and B viruses with mean IC50s of 0.67, 0.9, 1.34 and 13 nM, respectively[1].
Web ID
– HY-13317
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Molecular Formula
– C16H28N2O4
Citations
– Antiviral Res. 2016 Mar;127:68-78. |Food Funct. 2016 Apr 20;7(4):2052-9. |Phytochemistry. 2023 Aug 17;113829.|Virology. 2023 Dec 2, 109954.|Antiviral Res. 2020 Apr;176:104751. |Arch Pharm Res. 2018 Jun;41(6):664-676.|Bioeng Transl Med. 2020 Dec 1;6(1):e10196.|Biomed Pharmacother. 2018 Jan;97:385-394. |bioRxiv. 2023 Aug 12.|Biosci Biotechnol Biochem. 2020 Apr;84(4):774-779.|Cell Prolif. 2021 Jan;54(1):e12953.|Chemosphere. 2015 Jul;131:41-7.|Front Cell Dev Biol. 17 December 2021.|Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Transmissores de Hematozoários. 2020 Sep.|Inflammation. 2023 Aug 21.|Int J Mol Sci. 2019 Dec 12;20(24):6261.|Int J Mol Sci. 2022 Apr 1;23(7):3940.|J Ethnopharmacol. 2023 Oct 6:117290.|J Med Virol. 2023 Jul;95(7):e28968.|Lab Invest. 2020 Dec;100(12):1602-1617.|Sci Rep. 2021 Aug 11;11(1):16293.|Signal Transduct Target Ther. 2021 Apr 24;6(1):165.|Virology. 2020 Jun;545:1-9.|Viruses. 2018 Jun 13;10(6). pii: E325.
References
– [1]O Ferraris, et al. Sensitivity of Influenza Viruses to Zanamivir and Oseltamivir: A Study Performed on Viruses Circulating in France Prior to the Introduction of Neuraminidase Inhibitors in Clinical Practice. Antiviral Res. 2005 Oct;68(1):43-8.|[2]Smee DF, et al. Activities of JNJ63623872 and oseltamivir against influenza A H1N1pdm and H3N2 virus infections in mice. Antiviral Res. 2016 Dec;136:45-50. |[3]Ilyushina NA, et al. Amantadine-oseltamivir combination therapy for H5N1 influenza virus infection in mice. Antivir Ther. 2007;12(3):363-70. |[4]Ilyushina NA, et al. Oseltamivir-ribavirin combination therapy for highly pathogenic H5N1 influenza virus infection in mice. Antimicrob Agents Chemother. 2008 Nov;52(11):3889-97. |[5]Smee DF, et al. Combinations of oseltamivir and peramivir for the treatment of influenza A (H1N1) virus infections in cell culture and in mice. Antiviral Res. 2010 Oct;88(1):38-44.
CAS Number
– 196618-13-0
Molecular Weight
– 312.40
Compound Purity
– 95.0
SMILES
– O=C(OCC)C1=C[C@H]([C@@H]([C@H](C1)N)NC(C)=O)OC(CC)CC
Clinical Information
– Launched
Research Area
– Infection
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Influenza Virus
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
