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Norbormide

$739

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Products Details

Product Description

– Norbormide shows vasoconstrictor activity by blocking calcium channel. The activity of Norbormide is species- and tissue-specific, endothelium independent, and is restricted to the peripheral arteries of rat. Norbormide is also a toxicant, and the oral LD50s in mouse, hamster, guinea pig and rabbit are 2250, 140, 620, and 1000 mg/kg[1].

Web ID

– HY-122331

Shipping

– Room temperature

Molecular Formula

– C33H25N3O3

References

– [1]Bova S, et al. Norbormide: a calcium entry blocker with selective vasoconstrictor activity in rat peripheral arteries. Cardiovasc Drug Rev. 2001 Fall;19(3):226-33.

CAS Number

– 991-42-4

Molecular Weight

– 511.57

SMILES

– OC(C1=CC=CC=C1)(C2=CC=CC=N2)C3=CC4/C(C3[C@H](C(N5)=O)[C@@H]4C5=O)=C(C6=CC=CC=N6)/C7=CC=CC=C7

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease

Solubility

– 10 mM in DMSO

Target

– Calcium Channel

Pathway

– Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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